Recombinant Human KREMEN1, Fc-tagged KREMEN1-633H

Recombinant Human KREMEN1, Fc-tagged

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Recombinant Human KREMEN1, Fc-tagged

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Cat.No. : KREMEN1-633H
Product Overview : The recombinant human KREMEN1-Fc fusion is expressed as a 593 amino acid protein consisting of Arg21 - Gly375 region of KREMEN1 (Uniprot Accession #Q96MU8-3) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier and preservative free).
Bio-activity : Recombinant KREMEN1-Fc binds human Dkk1 with high affinity (apparent KD< 10 nM)
Molecular Mass : Calculated molecular mass (kDa): 65.8; Estimated by SDS-PAGE under reducing condition (kDa): 80-90.
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >90% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : KREMEN1 kringle containing transmembrane protein 1 [ Homo sapiens ]
Official Symbol : KREMEN1
Synonyms : KREMEN1; kringle containing transmembrane protein 1; KREMEN, kringle containing transmembrane protein; kremen protein 1; KRM1; dickkopf receptor; kringle-coding gene marking the eye and the nose; kringle domain-containing transmembrane protein 1; kringle-containing protein marking the eye and the nose; KREMEN; FLJ31863;
Gene ID : 83999
mRNA Refseq : NM_001039570
Protein Refseq : NP_001034659
MIM : 609898
UniProt ID : Q96MU8
Chromosome Location : 22q12.1
Pathway : Wnt signaling network, organism-specific biosystem;
Function : protein binding;

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