Active Recombinant Human TNFRSF12A, Fc-tagged, Biotinylated
Cat.No. : | TNFRSF12A-709H |
Product Overview : | The recombinant human TWEAKR-Fc fusion is expressed as a 281 amino acid protein consisting of Glu28- Pro80 region of TWEAKR (UniProt accession #Q9NP84) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligand TWEAK/TNFSF12 and inhibits TWEAK-mediated signaling activities including TWEAK--induced apoptosis in HT-29 human colon cancer cells and proliferation of human umbilical vein endothelial cells (HUVECs). |
Molecular Mass : | Calculated molecular mass (kDa): 31.1; Estimated by SDS-PAGE under reducing condition (kDa): ~40 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition. |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | TNFRSF12A tumor necrosis factor receptor superfamily, member 12A [ Homo sapiens ] |
Official Symbol : | TNFRSF12A |
Synonyms : | TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; tumor necrosis factor receptor superfamily member 12A; CD266; FN14; TweakR; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14; TWEAKR; |
Gene ID : | 51330 |
mRNA Refseq : | NM_016639 |
Protein Refseq : | NP_057723 |
MIM : | 605914 |
UniProt ID : | Q9NP84 |
Chromosome Location : | 16p13.3 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
TNFRSF12A-441H | Recombinant Human TNFRSF12A Protein, His&GST-tagged | +Inquiry |
TNFRSF12A-471H | Recombinant Human TNFRSF12A Protein, Fc-tagged | +Inquiry |
TNFRSF12A-1646R | Recombinant Rhesus Monkey TNFRSF12A Protein, hIgG1 tagged | +Inquiry |
TNFRSF12A-312H | Recombinant Active Human TNFRSF12A Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Tnfrsf12a-42M | Active Recombinant Mouse Fn-14, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF12A-1560HCL | Recombinant Human TNFRSF12A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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