Recombinant Mouse Pdcd1lg2, Fc-tagged, Biotinylated Pdcd1lg2-722M

Recombinant Mouse Pdcd1lg2, Fc-tagged, Biotinylated

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Recombinant Mouse Pdcd1lg2, Fc-tagged, Biotinylated

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Cat.No. : Pdcd1lg2-722M
Product Overview : The recombinant mouse PD-L2-Fc fusion is expressed as a 438 amino acid protein consisting of Leu20 - Thr220 region of mouse PD-L2 (UniProt accession #Q9WUL5) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Mouse
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its receptor PD-1 in a functional ELISA. Blocks the ligand PD-L1"s and PD-L2"s binding to its receptor and mediated signaling activity. Shows cross-species binding to human PD-1.
Molecular Mass : Calculated molecular mass 49.2 kDa; estimated by SDS-PAGE under reducing condition ~60 kDa (probably due to glycosylation)
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : Pdcd1lg2 programmed cell death 1 ligand 2 [ Mus musculus ]
Official Symbol : Pdcd1lg2
Synonyms : PDCD1LG2; programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2; Btdc; B7-DC; PD-L2; F730015O22Rik; MGC124039; MGC124040;
Gene ID : 58205
mRNA Refseq : NM_021396
Protein Refseq : NP_067371
MIM :
UniProt ID :
Pathway : Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;
Function : protein binding; receptor activity;

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