Recombinant Human RNASEL protein, MYC/DDK-tagged
Cat.No. : | RNASEL-39H |
Product Overview : | Recombinant Human RNASEL(His19-Glu563) fussed with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 83.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | RNASEL ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) [ Homo sapiens ] |
Official Symbol : | RNASEL |
Synonyms : | RNASEL; ribonuclease L (2,5-oligoisoadenylate synthetase-dependent); PRCA1, prostate cancer 1 , RNS4; 2-5A-dependent ribonuclease; RNase L; ribonuclease 4; 2-5A-dependent RNase; interferon-induced 2-5A-dependent RNase; 2,5-oligoisoadenylate synthetase-dependent; RNS4; PRCA1; MGC104972; MGC133329; DKFZp781D08126; |
Gene ID : | 6041 |
mRNA Refseq : | NM_021133 |
Protein Refseq : | NP_066956 |
MIM : | 180435 |
UniProt ID : | Q05823 |
Chromosome Location : | 1q25 |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem; Influenza A, organism-specific biosystem; |
Function : | ATP binding; RNA binding; endoribonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; metal ion binding; nucleotide binding; protein kinase activity; transferase activity, transferring phosphorus-containing groups; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (5)
Ask a questionSome studies have suggested that dietary factors, such as vitamin E and selenium, may influence RNASEL activity.
RNASEL expression and activity are regulated by various factors, including cytokines and viral infections.
Potential side effects may include alterations in immune response and potential impact on RNA degradation processes.
Yes, variations in the RNASEL gene have been linked to differences in the response to antiviral therapies.
Some studies have suggested a potential link between RNASEL protein and autoimmune diseases, but more research is needed to fully understand this relationship.
Customer Reviews (3)
Write a reviewI am certain that the RNASEL protein will play a pivotal role in facilitating robust and insightful research, providing the assurance of reliable and consistent results.
The excellent technical support provided by the manufacturer can solve my problem.
Whether I am studying protein-protein interactions, investigating cellular pathways, or examining protein folding dynamics, the RNASEL protein consistently delivers exceptional performance and precise outcomes.
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