"ATP4A" Related Products

Recombinant Human ATP4A protein, His-tagged

Cat.No.: ATP4A-19H
Product Overview: Recombinant Human ATP4A(Leu798~Gly896) fused with His tag at N-terminal was expressed in E. coli.
Description: The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase.
Source: E. coli
Species: Human
Tag: His
Form: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass: 12.7kDa
AA Sequence: MGHHHHHHSG SEF-LTPYLIY ITVSVPLPLG CITILFIELC TDIFPSVSLA YEKAESDIMH LRPRNPKRDR LVNEPLAAYS YFQIGAIQSF AGFTDYFTAM AQEGWFPLLC VG
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: SDS-PAGE; WB; ELISA; IP.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name: ATP4A ATPase, H+/K+ exchanging, alpha polypeptide [ Homo sapiens ]
Official Symbol: ATP4A
Synonyms: ATP6A
Gene ID: 495
mRNA Refseq: NM_000704.2
Protein Refseq: NP_000695
MIM: 137216
UniProt ID: P20648
Chromosome Location: 19q13.1
Pathway: Collecting duct acid secretion, organism-specific biosystem;Collecting duct acid secretion, conserved biosystem;Gastric acid secretion, organism-specific biosystem;Gastric acid secretion, conserved biosystem;Ion channel transport, organism-specific biosystem;Ion transport by P-type ATPases, organism-specific biosystem;Oxidative phosphorylation, organism-specific biosystem;
Function: ATP binding;hydrogen:potassium-exchanging ATPase activity;magnesium ion binding;protein heterodimerization activity;

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