Active Recombinant Human DUSP6 & MAPK14 protein

• Cat.No.: DUSP6 & MAPK14-631H
• Product Overview: Recombinant Human DUSP6 & MAPK14 was expressed in Insect cells.

Specification

• Description: MKP-3 (MAP Kinase Phosphatase-3, DUSP-6, PYST1) has an N-terminal MAP kinase binding domain. Co-expressing MKP-3 with p38 MAP kinase results in increased phosphatase activity compared to MKP-3 expressed alone.
• Source: Insect cells
• Species: Human
• Form: Liquid. In 20mM TRIS/HCl, pH 8.0, 200mM NaCl, 5mM DTT, 0.1 % Tween-20, 10% glycerol.
• Bio-activity: ≥10 U/µg assayed by 3-O-methyl fluorescein phosphate (OMFP) hydrolysis at 30 centigrade.
• Molecular Mass: 42 kDa / 41 kDa
• Purity: ≥90% (SDS-PAGE)
• Storage: Store at -80 centigrade

Gene Information

• Gene Name: DUSP6 dual specificity phosphatase 6 [ Homo sapiens ]
• Official Symbol: DUSP6
• Synonyms: DUSP6; dual specificity phosphatase 6; dual specificity protein phosphatase 6; MKP 3; PYST1; MAP kinase phosphatase 3; dual specificity protein phosphatase PYST1; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 3; MKP3
• Gene ID: 1848
• mRNA Refseq: NM_001946
• Protein Refseq: NP_001937
• MIM: 602748
• UniProt ID: Q16828
• Chromosome Location: 12q22-q23
• Pathway: Activated TLR4 signalling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; ERK/MAPK targets, organism-specific biosystem; ERKs are inactivated, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: MAP kinase tyrosine/serine/threonine phosphatase activity; hydrolase activity; protein tyrosine phosphatase activity