Recombinant Human UGCG protein, GST-tagged
Cat.No. : | UGCG-3581H |
Product Overview : | Recombinant Human UGCG(1 a.a. - 394 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
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Description : | Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transciption is upregulated during keratinocyte differentiation. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 71.3 kDa |
AA Sequence : | MALLDLALEGMAVFGFVLFLVLWLM HFMAIIYTRLHLNKKATDKQPYSKL PGVSLLKPLKGVDPNLINNLETFFE LDYPKYEVLLCVQDHDDPAIDVCKK LLGKYPNVDARLFIGGKKVGINPKI NNLMPGYEVAKYDLIWICDSGIRVI PDTLTDMVNQMTEKVGLVHGLPYVA DRQGFAATLEQVYFGTSHPRYYISA NVTGFKCVTGMSCLMRKDVLDQAGG LIAFAQYIAEDYFMAKAIADRGWRF AMSTQVAMQNSGSYSISQFQSRMIR WTKLRINMLPATIICEPISECFVAS LIIGWAAHHVFRWDIMVFFMCHCLA WFIFDYIQLRGVQGGTLCFSKLDYA VAWFIRESMTIYIFLSALWDPTISW RTGRYRLRCGGTAEEILDV |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | UGCG UDP-glucose ceramide glucosyltransferase [ Homo sapiens ] |
Official Symbol : | UGCG |
Synonyms : | UGCG; UDP-glucose ceramide glucosyltransferase; ceramide glucosyltransferase; GCS; glucosylceramide synthase; GLCT-1; UDP-glucose:N-acylsphingosine D-glucosyltransferase; GLCT1; |
Gene ID : | 7357 |
mRNA Refseq : | NM_003358 |
Protein Refseq : | NP_003349 |
MIM : | 602874 |
UniProt ID : | Q16739 |
Chromosome Location : | 9q31 |
Pathway : | Glycosphingolipid metabolism, organism-specific biosystem; IL2 signaling events mediated by PI3K, organism-specific biosystem; Lactosylceramide biosynthesis, organism-specific biosystem; Lactosylceramide biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; |
Function : | ceramide glucosyltransferase activity; transferase activity, transferring glycosyl groups; |
Products Types
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UGCG-3580H | Recombinant Human UGCG protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
UGCG-517HCL | Recombinant Human UGCG 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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