Recombinant Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4
Cat.No. : | KIR2DS4-147H |
Product Overview : | Recombinant KIR2DS4 protein produced in E.Coli is a single, non-glycosylated polypeptide chain and was purified by FPLC gel-filtration chromatography (202 aa, 22.2 kDa). |
- Specification
- Gene Information
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Cat. No. : | KIR2DS4-147H |
Description : | An activating Killer Cell Ig-like Receptor(KIR, previously called p50 KIR, p50.3, cl39, or KAR-K1), which may recognize class I MHC molecules. The protein coding region of the extracellular domain of KIR2DS4(amino acids 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DS4 was overexpressed as insoluble protein aggregates(inclusion bodies). The recombinant KIR2DS4 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. |
Source : | Escherichia Coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 7.5). |
Molecular Weight : | 22.2 kDa (202 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Amino acid Sequence : | MEGVHRKPSF LALPGHLVKS EETVILQCWS DVMFEHFLLH REGKFNNTLH LIGEHHDGVS KANFSIGPMM PVLAGTYRCY GSVPHSPYQL SAPSDPLDMV IIGLYEKPSL SAQPGPTVQA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAVRSINGTF QADFPLGPAT HGGTYRCFGS FRDAPYEWSN SSDPLLVSVT GN |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 [ Homo sapiens ] |
Synonyms : | KIR2DS4; KIR1D; KIR412; KKA3; MGC120019; MGC125315; MGC125317; NKAT-8; NKAT8; PAX; cl-39; Killer cell immunoglobulin-like receptor; nkat8; CD158I; CD158i; CL-17; CD158 antigen-like family member I; CD158i antigen; KIR antigen 2DS4; MHC class I NK cell receptor; Natural killer-associated transcript 8; P58 natural killer cell receptor clone CL-39; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4; killer inhibitory receptor 4-1-2; natural killer cell inhibitory receptor; p58 NK receptor. |
Gene ID : | 3809 |
mRNA Refseq : | NM_012314 |
Protein Refseq : | NP_036446 |
MIM : | 604955 |
UniProt ID : | P43632 |
Chromosome Location : | 19q13.4 |
Pathway : | Antigen processing and presentation. |
Function : | receptor activity. |
Products Types
◆ Recombinant Protein | ||
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KIR2DS4-1340H | Recombinant Human KIR2DS4 Protein (Gln22-Ser302), N-His tagged | +Inquiry |
KIR2DS4-4342H | Recombinant Human KIR2DS4 Protein (Met1-His245), C-His tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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