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Recombinant Human AMBP

Cat.No.: AMBP-230H
Product Overview: Recombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5.
Description: This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
Source: Pichia Pastoris.
Species: Human
Form: Sterile Filtered solution. Formulated in 1X PBS.
Bio-activity: Greater than 3000U/mg as measured by BAEE method.
Molecular Mass: 20 kDa
AA Sequence: AVLPQEEEGS GGGQLVTEVT KKEDSCQLGY SAGPCMGMTS RYFYNGTSMACETFQYGGCM GNGNNFVTEK ECLQTCRTVA ACNLPIVRGP CRAFIQLWAFDAVKGKCVLF PYGGCQGNGN KFYSEKECRE YCGVPGDGDE ELL.
Purity: Greater than 98.0% as determined by RP-HPLC and FPLC.
Storage: Ulinastatin although stable at 15°C for 2 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles.
Gene Name: AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens (human) ]
Official Symbol: AMBP
Synonyms: AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; alpha-1-microglobulin/bikunin precursor; protein AMBP; bikunin; uristatin; protein HC; trypstatin; uronic-acid-rich protein; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; complex-forming glycoprotein heterogeneous in charge
Gene ID: 259
mRNA Refseq: NM_001633
Protein Refseq: NP_001624
MIM: 176870
UniProt ID: P02760
Chromosome Location: 9q32-q33
Pathway: Binding and Uptake of Ligands by Scavenger Receptors; Scavenging of Heme from Plasma
Function: IgA binding; calcium channel inhibitor activity; calcium oxalate binding

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