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Recombinant Human AMBP

Cat.No. : AMBP-230H
Product Overview : Recombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5.
Description : This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
Source : Pichia Pastoris.
Species : Human
Form : Sterile Filtered solution. Formulated in 1X PBS.
Bio-activity : Greater than 3000U/mg as measured by BAEE method.
Molecular Mass : 20 kDa
AA Sequence : AVLPQEEEGS GGGQLVTEVT KKEDSCQLGY SAGPCMGMTS RYFYNGTSMACETFQYGGCM GNGNNFVTEK ECLQTCRTVA ACNLPIVRGP CRAFIQLWAFDAVKGKCVLF PYGGCQGNGN KFYSEKECRE YCGVPGDGDE ELL.
Purity : Greater than 98.0% as determined by RP-HPLC and FPLC.
Storage : Ulinastatin although stable at 15°C for 2 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles.
Publication :
Gene Name : AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens (human) ]
Official Symbol : AMBP
Synonyms : AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; alpha-1-microglobulin/bikunin precursor; protein AMBP; bikunin; uristatin; protein HC; trypstatin; uronic-acid-rich protein; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; complex-forming glycoprotein heterogeneous in charge
Gene ID : 259
mRNA Refseq : NM_001633
Protein Refseq : NP_001624
MIM : 176870
UniProt ID : P02760
Chromosome Location : 9q32-q33
Pathway : Binding and Uptake of Ligands by Scavenger Receptors; Scavenging of Heme from Plasma
Function : IgA binding; calcium channel inhibitor activity; calcium oxalate binding

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