Active Recombinant Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow

• Cat.No.: MYL2-235H
• Product Overview: Recombinant Human VMLC protein produced inE.Coliencodes full length amino acids.

Specification

• Cat. No.: MYL2-235H
• Description: VMLC is a subunit of the heterohexameric myosin protein, which modulates striated muscle contraction in response to phosphorilation by MLCK ( myosin light chain kinase).
• Source: Recombinant full length human VMLC protein expressed inE.coli.
• Formulation: 2x50ug/33µl purified human VMLC protein at 1.52mg/ml in 10mM Tris –HCI, 1mM EDTA PH 7.5.
• Application and suggested dilutions: •ELISA •Inhibition Assays •Western Blotting
• Activity: Assayed for phosphorilation by MLCK.
• Storage & stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: MYL2 myosin, light chain 2, regulatory, cardiac, slow [ Homo sapiens ]
• Synonyms: MYL2; myosin, light chain 2, regulatory, cardiac, slow; MLC-2; MLC-2v; CMH10; DKFZp779C0562; slow cardiac myosin regulatory light chain 2; RLC of myosin; myosin light chain 2; regulatory light chain of myosin; cardiac ventricular myosin light chain 2; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin regulatory light chain 2, ventricular/cardiac muscle isoform
• Gene ID: 4633
• mRNA Refseq: NM_000432
• Protein Refseq: NP_000423
• MIM: 160781
• UniProt ID: P10916
• Chromosome Location: 12q24.11
• Pathway: Focal adhesion; Hypertrophic cardiomyopathy (HCM); Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Tight junction;Muscle contraction
• Function: actin monomer binding; calcium ion binding; motor activity; myosin heavy chain binding; protein binding; structural constituent of muscle