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Recombinant Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow

Cat. No.: MYL2-235H
Product Overview: Recombinant Human VMLC protein produced inE.Coliencodes full length amino acids.
Description: VMLC is a subunit of the heterohexameric myosin protein, which modulates striated muscle contraction in response to phosphorilation by MLCK ( myosin light chain kinase).
Source: Recombinant full length human VMLC protein expressed inE.coli.
Formulation: 2x50ug/33µl purified human VMLC protein at 1.52mg/ml in 10mM Tris –HCI, 1mM EDTA PH 7.5.
Application and suggested dilutions: •ELISA •Inhibition Assays •Western Blotting
Activity: Assayed for phosphorilation by MLCK.
Storage & stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: MYL2 myosin, light chain 2, regulatory, cardiac, slow [ Homo sapiens ]
Synonyms: MYL2; myosin, light chain 2, regulatory, cardiac, slow; MLC-2; MLC-2v; CMH10; DKFZp779C0562; slow cardiac myosin regulatory light chain 2; RLC of myosin; myosin light chain 2; regulatory light chain of myosin; cardiac ventricular myosin light chain 2; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Gene ID: 4633
mRNA Refseq: NM_000432
Protein Refseq: NP_000423
MIM: 160781
UniProt ID: P10916
Chromosome Location: 12q24.11
Pathway: Focal adhesion; Hypertrophic cardiomyopathy (HCM); Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Tight junction;Muscle contraction
Function: actin monomer binding; calcium ion binding; motor activity; myosin heavy chain binding; protein binding; structural constituent of muscle

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