"CDH2" Related Products

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Recombinant Human Cadherin 2, Type 1, N-cadherin (Neuronal)

Cat. No. : CDH2-87H
Product Overview : Recombinant Human Cadherin-N protein 741-907 a.a. expressed inE.coli,43 kDa.
Description : Cadherins comprise a family of Ca+ dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains.
Source : E.coli
Presentation : Recombinant Human Cadherin-N protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.
Applications : •ELISA •Inhibition Assays •Western Blotting
Storage : Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name : CDH2 cadherin 2, type 1, N-cadherin (neuronal) [ Homo sapiens ]
Synonyms : CDH2; cadherin 2, type 1, N-cadherin (neuronal); CDHN; NCAD; CD325; CDw325; cadherin 2, type 1; N-cadherin 1; neural cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal; 5` partial; N-cadherin; Cadherin-2;CD325 antigen
Gene ID : 1000
mRNA Refseq : NM_001792
Protein Refseq : NP_001783
MIM : 114020
UniProt ID : P19022
Chromosome Location : 18q12.1
Pathway : Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cell adhesion molecules (CAMs); Cell-cell adhesion systems
Function : RPTP-like protein binding; beta-catenin binding; calcium ion binding; protein kinase binding; protein phosphatase binding

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