Recombinant Human Troponin C Type 1 (Slow)
Cat.No. : | TNNC1-138H |
Product Overview : | Recombinant Human troponin C type 1 (slow) produced inE. Coliis a single, non-glycosylated, polypeptide chain. The TNC has a molecular mass of 18,020 Dalton. The TNC is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNNC1-138H |
Description : | Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and Troponin C. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin. Troponin T and Troponin I are presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT recomplexed in vitro under appropriate conditions. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered colourless liquid formualtion. |
Formulation : | Each mg/ml of protein (0.5mg/ml) contains 50% glycerol. |
Purity : | Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained. |
Dimers And Aggregates : | Less than 1% as determined by silver stained SDS-PAGE gel analysis. |
Endotoxin : | Less than 0.1 ng/µg (IEU/µg) ofrHuTNC. |
Applications : | Immunoassays and western blot. |
Stability : | RHuTNC although stable at 10℃ for 7 days, should be stored desiccated below -18℃. Please prevent freeze-thaw cycles. |
Gene Name : | TNNC1 troponin C type 1 (slow) [ Homo sapiens ] |
Synonyms : | TNNC1; troponin C type 1 (slow); TNC; TNNC; CMD1Z; troponin C, slow; Troponin C, slow skeletal and cardiac muscles; TN-C; cardiac troponin C; troponin C1, slow; slow twitch skeletal/cardiac muscle troponin C |
Gene ID : | 7134 |
mRNA Refseq : | NM_003280 |
Protein Refseq : | NP_003271 |
MIM : | 191040 |
UniProt ID : | P63316 |
Chromosome Location : | 3p21.3-p14.3 |
Pathway : | Calcium signaling pathway; Cardiac muscle contraction; Hypertrophic cardiomyopathy (HCM); Muscle contraction |
Function : | actin filament binding; calcium ion binding; calcium- dependent protein binding; protein homodimerization activity; troponin I binding; troponin T binding |
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◆ Native Protein | ||
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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