"SYT1" Related Products


Recombinant Human Synaptotagmin I, GST-tagged

Cat. No. : SYT1-437H
Product Overview : Recombinant Human synaptotagmin I expressed inE.coliwas cloned with a N-terminal-GST tag and a linker. It consists of the human Synaptotagmin I (residues 96-421, swissprot accession P21579). The GST-tag is cleaved during purification. The protein is mutated in the position I367T and contains a deletion of three amino acids 117A, 118L, and 119K. MW = 37.8 kDa.
Description : Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.
Source : Escherichia Coli.
Purity : > 95% by SDS-PAGE. The protein was observed as a single band migrating at amolecular weight of (< 45 kDa).
Supplied As : 1.0mg/ml in PBS pH7.3.The concentration is calculated from the absorbance at 280nm (e280 = 31150 M-1 cm-1).
Characteristics : Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum of 500 μM.
Storage : -20ºC. The protein is stable at 4ºC for at least 2 weeks and at 25ºC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20ºC. Avoid repeated freeze/defrost cycles.
Gene Name : SYT1 synaptotagmin I [ Homo sapiens ]
Synonyms : SYT1; synaptotagmin I; synaptotagmin 1; P65; SYT; SVP65; DKFZp781D2042; Synaptotagmin-1; DKFZp781D2042; OTTHUMP00000166064; SytI
Gene ID : 6857
mRNA Refseq : NM_001135805
Protein Refseq : NP_001129277
MIM : 185605
UniProt ID : P21579
Chromosome Location : 12cen-q21
Pathway : Botulinum neurotoxicity; Synaptic Transmission
Function : calcium ion binding; calcium-dependent protein binding; calmodulin binding; identical protein binding; low-density lipoprotein receptor binding; phosphatidylinositol binding; phospholipid binding; syntaxin-1 binding; transporter activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.