Active Recombinant Full Length Human SYT1 Protein, C-Flag-tagged

• Cat.No.: SYT1-426HFL
• Product Overview: Recombinant Full Length Human SYT1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: MS digestion standard
• Molecular Mass: 47.4 kDa
• AA Sequence: MVSESHHEALAAPPVTTVATVLPSN ATEPASPGEGKEDAFSKLKEKFMNE LHKIPLPPWALIAIAIVAVL LVLTCCFCICKKCLFKKKNKKKGKE KGGKNAINMKDVKDLGKTMKDQALK DDDAETGLTDGEEKEEPKEE EKLGKLQYSLDYDFQNNQLLVGIIQ AAELPALDMGGTSDPYVKVFLLPDK KKKFETKVHRKTLNPVFNEQ FTFKVPYSELGGKTLVMAVYDFDRF SKHDIIGEFKVPMNTVDFGHVTEEW RDLQSAEKEEQEKLGDICFS LRYVPTAGKLTVVILEAKNLKKMDV GGLSDPYVKIHLMQNGKRLKKKKTT IKKNTLNPYYNESFSFEVPF EQIQKVQVVVTVLDYDKIGKNDAIG KVFVGYNSTGAELRHWSDMLANPRR PIAQWHTLQVEEEVDAMLAV
  KKTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: SYT1 synaptotagmin 1 [ Homo sapiens (human) ]
• Official Symbol: SYT1
• Synonyms: P65; SYT; BAGOS; SVP65
• Gene ID: 6857
• mRNA Refseq: NM_001135806.2
• Protein Refseq: NP_001129278.1
• MIM: 185605
• UniProt ID: P21579

Q&As

How can SYT1 be used as a biomarker in clinical practice?

In clinical practice, the expression level of SYT1 can be detected to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of neurological diseases, the expression level of SYT1 can help doctors determine the type, stage and prognosis of the disease, and guide the choice of treatment regimen.

How is SYT1 protein related to viral infection?

Studies have shown that SYT1 protein can participate in the regulation of antiviral immune response and affect the course of viral infection.

Is SYT1 protein associated with autoimmune diseases?

SYT1 protein plays an important role in the pathogenesis of certain autoimmune diseases.

Is SYT1 protein associated with cardiovascular disease?

Studies have shown that SYT1 protein may be associated with the pathogenesis of cardiovascular diseases such as atherosclerosis and myocardial infarction.

How can I improve the nutritional status of SYT1 protein through diet?

There is no conclusive evidence that diet can improve the nutritional status of SYT1 protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.

What is the current progress in drug development for SYT1?

Drug development for SYT1 is currently in clinical trials, including small molecule inhibitors against SYT1 and inhibitors against the SYT1 signaling pathway.