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Recombinant Human Growth Hormone 1

Cat. No.: GH1-80H
Product Overview: Recombinant Human Growth Hormone 1 encoding the human growth hormone protein sequence (containing the signal peptide sequence and the mature growth hormone sequence) was expressed in modifiedhuman 293 cells.
Description: Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones. Its activity is required for normal human growth and development. It regulates an extensive variety of physiological functions relating to human growth and metabolism, primarily by inducing the expression of insulin-like growth factor 1 (IGF-1). hGH is synthesized and secreted into the circulation by acidophilic or somatotropic cells of the anterior pituitary gland in response to hGH releasing hormone (HGHR) from the hypothalamus.
Source: Human 293 cells.
Amino Acid Sequence: FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF.
Molecular Mass: Growth Hormone migrates as a band with an apparent MW of 20 kDa in SDS-PAGE. This compares with the predicted molecular mass of 22.1 kDa.
pI: Unmodified Growth Hormone has a predicted pI of 5.27.
Purity: >95%, as determined by SDS-PAGE and visualized by silver stain.
Formulation: When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
Reconstitution: It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.
Storage: Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
Gene Name: GH1 growth hormone 1 [ Homo sapiens ]
Synonyms: GH1; growth hormone 1; GH; GHN; GH-N; hGH-N; IGHD1B; pituitary growth hormone
Gene ID: 2688
mRNA Refseq: NM_000515
Protein Refseq: NP_000506
UniProt ID: P01241
Chromosome Location: 17q22-q24
MIM: 139250
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction
Function: growth factor activity; growth hormone activity; growth hormone receptor binding; olactin receptor binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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