"ASF1A" Related Products

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Recombinant Human ASF1A, His-tagged

Cat. No. : ASF1A-508H
Product Overview : Recombinant human ASF1A, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 27 kDa (240aa).
Description : ASF1 anti-silencing function 1 homolog A, also known as ASF1A, belongs to H3/H4 family of histone chaperone proteins. ASF1A protein interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair. Deletion of ASF1A in yeast and Drosophila confers sensitivity to various DNA damaging agents and inhibitors of DNA replication, increases genomic instability and sister chromatid exchange, and activates the DNA damage checkpoint.
Source : E.coli.
Amino Acid Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAKV QVNNVVVLDN PSPFYNPFQF EITFECIEDL SEDLEWKIIY VGSAESEEYDQVLDSVLVGP VPAGRHMFVF QADAPNPGLI PDADAVGVTV VLITCTYRGQ EFIRVGYYVN NEYTETELRE NPPVKPDFSK LQRNILASNP RVTRFHINWE DNTEKLEDAE SSNPNLQSLL STDALPSASK GWSTSENSLN VMLESHMDCM.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method ).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : ASF1A ASF1 anti-silencing function 1 homolog A (S. cerevisiae) [ Homo sapiens ]
Synonyms : ASF1A; ASF1 anti-silencing function 1 homolog A (S. cerevisiae); CIA; CGI-98; HSPC146; DKFZp547E2110; ASF1 anti-silencing function 1 homolog A; CCG1-interacting factor A; anti-silencing function 1A; DKFZP547E2110; DKFZp547E2110
Gene ID : 25842
mRNA Refseq : NM_014034
Protein Refseq : NP_054753
MIM : 609189
UniProt ID : Q9Y294
Chromosome Location : 6q22.31
Function : chromatin binding; histone binding

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