Cat.No. :	ACVR2A-195H?
Product Overview :	Recombinant Human ACVR2A extracellular domain N-terminal segment (Met 1-Pro 134) (NP_001607.1), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
Source :	Human Cells
Species :	Human
Tag :	Fc
Form :	Lyophilized from sterile PBS, pH 7.4
Molecular Mass :	The recombinant human ACVR2A/Fc chimera is a disulfide-linked homodimer protein generated after removal of the signal peptide. The monomer comprises 352 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions.
Endotoxin :	< 1.0 eu per μg of the protein as determined by the LAL method.
Stability :	Samples are stable for up to twelve months from date of receipt at -70oC.
Storage :	Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4oC before opening to recover the entire contents.
Publication :	Combined detection of the ActRII‐Fc fusion proteins Sotatercept (ActRIIA‐Fc) and Luspatercept (modified ActRIIB‐Fc) in serum by means of immunoaffinity purification, tryptic digestion, and LC‐MS/MS

Gene Name :	ACVR2A activin A receptor, type IIA [ Homo sapiens ]
Official Symbol :	ACVR2A
Gene ID :	92
mRNA Refseq :	NM_001616
Protein Refseq :	NP_001607
MIM :	102581
UniProt ID :	P27037

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