Active Recombinant Human BMPR2 protein, His&hFc-tagged
Cat.No. : | BMPR2-133H |
Product Overview : | Recombinant Human BMPR2 protein(NP_001195.2)(Met1-Ile151), fused with His and hFc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His&hFc |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA.2. Immobilized human BMPR-II-Fc at 10 μg/mL (100 μl/well) can bind biotinylated human BMP2-Fc, The EC50 of biotinylated human BMP2-Fc is 80-110 ng/mL. |
Molecular Mass : | The recombinant human BMPR-II/Fc is a disulfide-linked homodimer. The reduced monomer consists of 373 amino acids and has a predicted molecular mass of 42 kDa. As a result of glycosylation, the apparent molecular mass of rh BMPR-II/Fc monomer migrates with an apparent molecular mass of 60-65 kDa in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Ile151 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) [ Homo sapiens ] |
Official Symbol : | BMPR2 |
Synonyms : | BMPR2; bone morphogenetic protein receptor, type II (serine/threonine kinase); PPH1, primary pulmonary hypertension 1; bone morphogenetic protein receptor type-2; BMPR II; BMPR3; BRK 3; T ALK; BMPR-2; BMP type-2 receptor; BMP type II receptor; type II activin receptor-like kinase; bone morphogenetic protein receptor type II; type II receptor for bone morphogenetic protein-4; BMR2; PPH1; BRK-3; T-ALK; BMPR-II; FLJ41585; FLJ76945; |
Gene ID : | 659 |
mRNA Refseq : | NM_001204 |
Protein Refseq : | NP_001195 |
MIM : | 600799 |
UniProt ID : | Q13873 |
Products Types
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BMPR2-377R | Recombinant Rhesus Macaque BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR2-451H | Recombinant Human BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR2-2707H | Recombinant Human BMPR2 Protein, MYC/DDK-tagged | +Inquiry |
BMPR2-1060M | Recombinant Mouse BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BMPR2-2717HCL | Recombinant Human BMPR2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionBMPR2 plays a significant role in PAH, influencing vascular cell proliferation and vascular remodeling.
Mutations in BMPR2 contribute to hereditary hemorrhagic telangiectasia, impacting vascular development.
Changes in BMPR2 signaling impact embryonic development, potentially resulting in congenital anomalies.
Dysregulation of BMPR2 affects renal function, potentially leading to kidney disease and dysfunction.
BMPR2 is key in bone morphogenetic protein signaling, crucial for bone growth and remodeling.
BMPR2 is involved in cardiovascular development, particularly affecting heart valve formation and function.
BMPR2 regulates cell proliferation and apoptosis, playing a role in tissue homeostasis.
Customer Reviews (3)
Write a reviewHigh-quality protein crystallography services, exceptional outcomes.
Critical expertise in protein engineering, unmatched service quality.
Swift and reliable protein sequencing, invaluable for our research.
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