Mitotic checkpoint serine/threonine-protein kinase BUB1


Home / Products / Others / Crystallography / Mitotic checkpoint serine/threonine-protein kinase BUB1

Mitotic checkpoint serine/threonine-protein kinase BUB1

BUB1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : CBCRY01
Background : The kinase(BUB1) functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Protein Classification : Transferase
Structure Weight : 42450.29 Da
Polymer : 1
Molecule : Mitotic checkpoint serine/threonine-protein kinase BUB1
Chain Length : 365 amino acids
MMDB ID : 68144
Source : Spodoptera frugiperda
Method : X-Ray Diffraction
Resolution : 2.31Å
Ligand Chemical Component : Adenosine-5"-triphosphate; chloride ion; Magnesium ion
Reference : Kang J, Yang M, Li B, Qi W, Zhang C, Shokat KM, Tomchick DR, Machius M, Yu H. Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.Mol Cell. 2008 Nov 7;32(3):394-405.
Gene Name : BUB1
Synonyms : BUB1A, BUB1L, hBUB1, BUB1 budding uninhibited by benzimidazoles 1 homolog; budding uninhibited by benzimidazoles 1; mitotic spindle checkpoint kinase; putative serine/threonine-protein kinase
UniProt ID : O43683
Gene ID : 699
Chromosome Location : 2q14
Function : nucleotide binding; protein kinase activity; protein serine/threonine kinase activity ; ATP binding; kinase activity; transferase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry

  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2022 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy