Mitotic arrest deficient 2


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Mitotic arrest deficient 2

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Cat. No. : CBCRY02
Background : MAD2 (mitotic arrest deficient 2) is one of the kinetochore protein present on the chromosome during cell division. It is involved in making sure all chromosomes are attached to the mitotic spindle before the beginning of anaphase.
Protein Classification : Cell Cycle
Structure Weight : 288687.00 Da
Polymer : 1
Molecule : Mitotic Spindle assembly checkpoint protein MAD2A
Chain Length : 206 amino acids
MMDB ID : 63130
Source : E.coli
Method : X-Ray Diffraction
Resolution : 1.95 Å
Ligand Chemical Component : Chloride ion, Magnesium ion, PE3, PE4, PEG
Reference : Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X. (2008) Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol. 6: E50
Gene Name : MAD2L1
Synonyms : HSMAD2; MAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like 1; MAD2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1
UniProt ID : Q13257
Gene ID : 4085
Chromosome Location : 4q27
Function : protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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