"Il28a" Related Products


Recombinant Murine Interleukin 28A

Cat. No.: II28A-992M
Product Overview: Recombinant Murine interleukin 28A produced inE.coliwas a 19.8kDa protein containing 175 amino acid residues.
Description: IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.
Source: E.coli.
Purity: >95% by SDS-PAGE and HPLC analysis.
Endotoxin Level: <0.1ng/μg of IFN II28A.
Stabilizer: None.
Formulation: Lyophilized.
Biologically Activity: Determined by its ability to activate STAT following receptor-ligand interaction.
Reconstitution: The human IFN-lambda-2 should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human IFN-lambda-2 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name: Il28a interleukin 28A [ Mus musculus ]
Synonyms: Il28a; interleukin 28A; Ifnl2; EG330496; IFN-lambda2; interferon-lambda2
Gene ID: 330496
mRNA Refseq: NM_001024673.2
Protein Refseq: NP_001019844.2
UniProt ID: Q4VK74
Chromosome Location: 7
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity

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