"NTF3 with TNFR" Related Products

The neurotrophin-3 and p75NTR symmetrical

Cat. No.: CBCRY18
Background: Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT.
Protein Classification: signaling protein
Structure Weight: 63861.22
Polymer: 1
Molecule: Neurotrophin-3
Chain Length: 119 amino acids
MMDB ID: 65479
Source: E.coli
Method: X-Ray Diffraction
Resolution: 2.6Å
Ligand Chemical Component: N-Acetyl-D-Glucosamine
Reference: Gong, Y., Cao, P., Yu, H.J., Jiang, T.(2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.Nature454: 789-793
Gene Name: NTF3
Synonyms: HDNF; MGC129711; NGF-2; NGF2; NT3; Nerve growth factor 2; neurotrophic factor; neurotrophin 3
UniProt ID: P20783
Chromosome Location: 12p13
Function: growth factor activity; nerve growth factor binding; neurotrophin receptor binding
Gene ID: 4804

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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