The neurotrophin-3 and p75NTR symmetrical


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The neurotrophin-3 and p75NTR symmetrical

NTF3 with TNFR Related Products

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Cat. No. : CBCRY18
Background : Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT.
Protein Classification : signaling protein
Structure Weight : 63861.22
Polymer : 1
Molecule : Neurotrophin-3
Chain Length : 119 amino acids
MMDB ID : 65479
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.6Å
Ligand Chemical Component : N-Acetyl-D-Glucosamine
Reference : Gong, Y., Cao, P., Yu, H.J., Jiang, T.(2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.Nature454: 789-793
Gene Name : NTF3
Synonyms : HDNF; MGC129711; NGF-2; NGF2; NT3; Nerve growth factor 2; neurotrophic factor; neurotrophin 3
UniProt ID : P20783
Chromosome Location : 12p13
Function : growth factor activity; nerve growth factor binding; neurotrophin receptor binding
Gene ID : 4804

Related Gene


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