Pyrroline-5-carboxylate Reductase 2
Cat.No. : | CBCRY25 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY25 |
Background : | Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor. The enzymatic cycle between P5C and proline is very important for the regulation of amino acid metabolism, intracellular redox potential, and apoptosis. |
Protein Classification : | Oxidoreductase |
Structure Weight : | 149791.08 Da |
Polymer : | 1 |
Molecule : | Pyrroline-5-carboxylate reductase 2 |
Chain Length : | 277 amino acids |
PDB ID : | 2GR9 |
MMDB ID : | 41570 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 3.1Å |
Ligand Chemical Component : | Magnesium ion; Sulfate ion |
Reference : | Meng, Z., Lou, Z., Liu, Z., Li, M., Zhao, X., Bartlam, M., Rao, Z. (2006) Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol. 359: 1364-1377 |
Gene Name : | PYCR2 |
Synonyms : | P5CR2; OTTHUMP00000035614; pyrroline 5-carboxylate reductase isoform; EC 1.5.1.2; P5C reductase 2; pyrroline-5-carboxylate reductase family, member 2; FLJ54750; RP4-559A3.4 |
UniProt ID : | Q96C36 |
Gene ID : | 29920 |
Chromosome Location : | 1q42.12 |
Function : | catalytic activity; binding; pyrroline-5-carboxylate reductase activity; Oxidoreductase activity |
Products Types
◆ Recombinant Protein | ||
PYCR2-1816H | Recombinant Human PYCR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pycr2-5271M | Recombinant Mouse Pycr2 Protein, Myc/DDK-tagged | +Inquiry |
PYCR2-3537R | Recombinant Rhesus Macaque PYCR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR2-4516R | Recombinant Rat PYCR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CRY20 | Recombinant Human Pyrroline-5-carboxylate Reductase 2 | +Inquiry |
◆ Lysates | ||
PYCR2-2647HCL | Recombinant Human PYCR2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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