"Fabp4" Related Products

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Recombinant Mouse Fatty Acid Binding Protein 4, Adipocyte, His-tagged

Cat. No.: Fabp4-1004M
Product Overview: Recombinant Mouse Fabp4 was produced inE.Colifused with a his tag.
Description: Fatty-acid binding protein 4(FABP4), also termed adipocyte fatty-acid binding protein (A-FABP), or aP2, is a novel adipocyte-expressed factor which accounted for ~6% of total cellular proteins. Several animal experiments suggested that FABP-4 plays a key role in the link between obesity and various features of metabolic syndrome. Mice with targeted disruption of FABP-4 accompany FABP-5 almost completely protect against diet-induced obesity, insulin resistance, dyslipidemia, type 2 diabetes, and fatty liver disease. Studies in human found FABP-4 serum levels were significantly increased in overweight and obese subjects, which predicted the risk to develop metabolic syndrome and type 2 diabetes. Additionally, serum FABP-4 levels were associated with carotid atherosclerosis and coronary artery disease.
Source: E.Coli.
Amino Acid Sequence: MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDLV TIRSESTFKN TEISFKLGVE FDEITADDRK VKSIITLDGG ALVQVQKWDG KSTTIKRKRD GDKLVVECVM KGVTSTRVYE RA
Form: Filtered (0.22 μm) and lyophilized in 1 mg/mL in PBS.
Purity: >95%.
Applications: ELISA, Western blotting, Immunoprecipitation
Reconstitution: Add deionized water to prepare a working stock solution of approximately 1 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage: Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing /thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Gene Name: Fabp4 fatty acid binding protein 4, adipocyte [ Mus musculus ]
Synonyms: Fabp4; fatty acid binding protein 4, adipocyte; Ap2; Lbpl; 422/aP2; ALBP/Ap2; adipocyte protein aP2; lipid binding protein-like
Gene ID: 11770
mRNA Refseq: NM_024406
Protein Refseq: NP_077717
UniProt ID: P04117
Chromosome Location: 313.9 cM
Pathway: PPAR signaling pathway
Function: Binding; lipid binding; transcription repressor activity; transporter activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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