"PNPLA2" Related Products

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Recombinant Human PNPLA2, His-tagged

Cat.No.: PNPLA2-322H
Product Overview: A DNA sequence encoding the human ATGL (Met1-Leu504) with 6 His tag on the N-Terminus was expressed in E. Coli. This protein was purified by Ni-NTA column.
Description: This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.
Source: E. Coli
Species: Human
Tag: His
Form: Lyophilized 100 ug human ATGL in 100 ul of TBS ( 20 mM Tris, 50mM NaCl, pH8.0 ), Carry free.
Molecular Mass: 73 KD
AA Sequence: human ATGL (Met1-Leu504)1 MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTRVSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQGYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVPEDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQLAGPAPLLST PAPEARPVIG ALGL 504
Purity: >90% in SDS-PAGE gel
Applications: Biology; ELISA
Storage: Store lyophilized protein at -20 °C or -70 °C. Lyophilized protein is stable for up to 6 months from date of receipt at - 20 °C to -70 °C. Upon reconstitution, this protein can be stored at -20 °C for a few weeks or at -70 °C in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.
Reconstitution: Add 500 ul deionized water to the vial to prepare a working stock solution at 200 ug/mL . Allow to set at least 30 minutes at 4 °C, mix well.
Gene Name: PNPLA2 patatin-like phospholipase domain containing 2 [ Homo sapiens ]
Official Symbol: PNPLA2
Synonyms: PNPLA2; patatin-like phospholipase domain containing 2; TGL; TTS2; PEDF-R; FP17548; TTS-2.2; DESNUTRIN; DKFZp667M109; 1110001C14Rik; triglyceride hydrolase; adipose triglyceride lipase; transport-secretion protein 2.2; pigment epithelium-derived factor; Patatin-like phospholipase domain-containing protein 2; EC 3.1.1.3; Adipose triglyceride lipase; Desnutrin; Transport-secretion protein 2; TTS2.2; Calcium-independent phospholipase A2; IPLA2-zeta; Pigment epithelium-derived factor
Gene ID: 57104
mRNA Refseq: NM_020376
Protein Refseq: NP_065109
MIM: 609059
UniProt ID: Q96AD5
Chromosome Location: 11p15.5
Pathway: Acyl chain remodeling of DAG and TAG; Acylglycerol degradation; Fatty Acid Beta Oxidation; Glycerolipid metabolism
Function: triglyceride lipase activity

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