Recombinant Human Perilipin 2, His-tagged
Cat.No. : | PLIN2-904H |
Product Overview : | Recombinant Human Perilipin 2 encoding the human adipose related protein (Met1- His437) was recombined with his tag at the N-Terminus. That was expressed inE. Coli, and purified by Ni-NTA column.MW=48.1KDa. |
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- Gene Information
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Cat. No. : | PLIN2-904H |
Description : | Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the earliest indications of adipocyte differentiation. |
Source : | E. Coli. |
Sequence : | Human adipose differentiation related protein (Met1-His437)1MASVAVDPQP SVVTRVVNLP LVSSTYDLMS SAYLSTKDQY PYLKSVCEMA ENGVKTITSV AMTSALPIIQ KLEPQIAVAN TYACKGLDRI EERLPILNQP STQIVANAKG AVTGAKDAVT TTVTGAKDSV ASTITGVMDK TKGAVTGSVE KTKSVVSGSI NTVLGSRMMQ LVSSGVENAL TKSELLVEQY LPLTEEELEK EAKKVEGFDL VQKPSYYVRL GSLSTKLHSR AYQQALSRVK EAKQKSQQTI SQLHSTVHLI EFARKNVYSA NQKIQDAQDK LYLSWVEWKR SIGYDDTDES HCAEHIESRT LAIARNLTQQ LQTTCHTLLS NIQGVPQNIQ DQAKHMGVMA GDIYSVFRNA ASFKEVSDSL LTSSKGQLQK MKESLDDVMD YLVNNTPLNW LVGPFYPQLT ESQNAQDQGA EMDKSSQETQ RSEHKTH 437. |
Purity : | >95% in SDS gel. |
Formulation : | Lyophilized 100 μg human Perilipin 2 in 50 μl of TBS (20 mM Tris, 50mM NaCl, pH8.0). Carry free. |
Application : | Cell biology, ELISA. |
Reconstitution : | Add 500 μl deionized water to the vial to prepare a working stock solution at 200μg/mL. Allow to set at least 30 minutes at 4°C, mix well. |
Storage : | Store lyophilized protein at -20°C or -70°C. Lyophilized protein is stable for up to 6 months from date of receipt at -70°C. Upon reconstitution, this protein can be stored at for a few weeks or at -70°C in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles. |
Publication : |
Aromatic Functionality of Target Proteins Influences Monomer Selection for Creating Artificial Antibodies on Plasmonic Biosensors. (2016)
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Gene Name : | PLIN2 perilipin 2 [ Homo sapiens ] |
Synonyms : | ADFP; ADRP; PLIN2; adipose differentiation-related protein; adipophilin; MGC10598; Adipose differentiation-related protein; Adipophilin; Perilipin 2 |
Gene ID : | 123 |
mRNA Refseq : | NM_001122 |
Protein Refseq : | NP_001113 |
MIM : | 103195 |
UniProt ID : | Q99541 |
Chromosome Location : | 9p22.1 |
Pathway : | Metabolism of lipids and lipoproteins |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
PLIN2-23H | Recombinant Human PLIN2 Protein (444 AA), N-8×His tagged | +Inquiry |
PLIN2-6848M | Recombinant Mouse PLIN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PLIN2-1707H | Recombinant Human PLIN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRP-3201H | Recombinant Human PLIN2 protein, His-tagged | +Inquiry |
PLIN2-62H | Recombinant Human Perilipin 2, T7-tagged | +Inquiry |
◆ Lysates | ||
PLIN2-3107HCL | Recombinant Human PLIN2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe interaction between PLIN2 and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways. These interactions can be influenced by a variety of factors, such as nutrients, hormones, and inflammatory factors.
Some studies have suggested that the expression level of PLIN2 may be associated with the occurrence and progression of cardiovascular disease. High levels of PLIN2 may be associated with an increased risk of cardiovascular diseases such as atherosclerosis, myocardial hypertrophy, and heart failure.
The function of PLIN2 can be studied through gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models of PLIN2 deletion or reduction to observe its effects on fat storage and breakdown, among other things.
PLIN2 plays an important role in obesity and diabetes. It may influence the development of obesity and diabetes by regulating adipocyte differentiation, insulin sensitivity, and lipid metabolism.
PLIN2 can be studied through overexpression techniques, such as the use of gene transduction or viral transduction. These techniques can increase the expression level of PLIN2 to observe its effects on fat storage and breakdown, among other things.
Some studies have shown that PLIN2 expression levels may be associated with obesity, diabetes, and cardiovascular disease, among others. High levels of PLIN2 may be associated with increased susceptibility to disease, while low levels of PLIN2 may be associated with decreased susceptibility to disease.
Customer Reviews (3)
Write a reviewOperation is simple and does not require complex operation steps.
Quality I use is very good and I have recommended this product to my colleagues and friends.
Sensitivity in Western blot is very high and low concentrations of the target protein can be detected.
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