Rho Guanine Nucleotide Exchange Factor 7
Cat.No. : | CBCRY28 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY28 |
Background : | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined. |
Protein Classification : | Signaling Protein |
Structure Weight : | 15255.28 Da |
Polymer : | 1 |
Molecule : | Rho guanine nucleotide exchange factor 7 |
Chain Length : | 61 amino acids |
PDB ID : | 2ESW |
MMDB ID : | 38672 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 2.01Å |
Ligand Chemical Component : | Chloride ion; Mercury ion |
Reference : | Li, X., Liu, X., Sun, F., Gao, J., Zhou, H., Gao, G.F., Bartlam, M., Rao, Z. (2006) Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor Biochem. Biophys. Res. Commun. 339: 407-414 |
Gene Name : | Arhgef7 |
Synonyms : | PIX; Cool; Pak3bp; cool-1; p85SPR; betaPix; p85Cool1; betaPix-b; betaPix-c; mKIAA0142; Arhgef7; PAK-interacting exchange factor beta; OTTMUSP00000023238; Pak3 binding protein; Pak interacting exchange factor; Dkfzp761k1021; kiaa0412; p50; p50bp; p85; pak3; pixb |
UniProt ID : | Q6XPA5 |
Gene ID : | 54126 |
Chromosome Location : | 8 A1.1 |
Function : | guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; protein binding |
Products Types
◆ Recombinant Protein | ||
ARHGEF7-3892H | Recombinant Human ARHGEF7 Protein, MYC/DDK-tagged | +Inquiry |
Arhgef7-1696M | Recombinant Mouse Arhgef7 Protein, Myc/DDK-tagged | +Inquiry |
ARHGEF7-703M | Recombinant Mouse ARHGEF7 Protein, His (Fc)-Avi-tagged | +Inquiry |
ARHGEF7-790H | Recombinant Human ARHGEF7 protein, GST-tagged | +Inquiry |
ARHGEF7-3594H | Recombinant Human ARHGEF7 protein, His-tagged | +Inquiry |
◆ Lysates | ||
ARHGEF7-8729HCL | Recombinant Human ARHGEF7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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