Polyadenylate-binding Protein 2 CBCRY37

Polyadenylate-binding Protein 2

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Polyadenylate-binding Protein 2

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Cat. No. : CBCRY37
Background : Poly(A) binding protein, nuclear 1, also known as PABPN1, is required for progressive and efficient polymerization of poly(A) tails on the 3" ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm.
Protein Classification : RNA binding protein
Structure Weight : 43445.20 Da
Polymer : 1
Molecule : Polyadenylate-binding protein 2
Chain Length : 96 amino acids
PDB ID : 3B4M
MMDB ID : 61872
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.82Å
Reference : Ge, H., Zhou, D., Tong, S., Gao, Y., Teng, M., Niu, L. (2008) Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins 71: 1539-1545
Gene Name : PABPN1
Synonyms : OPMD; PAB2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1
UniProt ID : Q86U42
Gene ID : 8106
Chromosome Location : 14q11.2-q13
Function : nucleotide binding; nucleic acid binding; RNA binding; protein binding

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