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Recombinant Myobacterium Tuberculosis Molecular Chaperone DnaK

Cat.No. : DnaK-1257H
Product Overview : Recombinant Mycobacterium Tuberculosis Dnak produced inE.Coliis a single, non-glycosylated polypeptide chain containing 625 amino acids and having a molecular mass of 66.7 kDa.
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  • Gene Information
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Cat. No. : DnaK-1257H
Description : DnaK, originally identified for its DNA replication by bacteriophage l in E. coli is the bacterial hsp70 chaperone. This protein is involved in the folding and assembly of newly synthesized polypeptide chains and in preventing the aggregation of stress-denatured proteins.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : The DnaK protein was lyophilized from a concentrated (1mg/ml) solution containing 10mM sodium phosphate buffer pH 7.4, 130mM sodium chloride and 2.5mM KCl.
Solubility : It is recommended to reconstitute the lyophilized DnaK in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability : Lyophilized DnaK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution DnaK should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Pathways : RNA degradation
Gene Name : dnaK molecular chaperone DnaK [ Mycobacterium tuberculosis H37Rv ]
Synonyms : Rv0350; molecular chaperone DnaK
Gene ID : 885946
Protein Refseq : NP_214864

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does DNAK protein interact with other cellular components? 06/03/2022

DNAK interacts with co-chaperones and client proteins, forming complexes that facilitate proper protein folding and function.

How is DNAK protein studied in a clinical laboratory setting? 05/03/2022

Laboratory techniques such as Western blotting and immunohistochemistry are commonly used to analyze DNAK protein expression and localization.

Can DNAK protein be targeted for drug development? 01/09/2022

Efforts are underway to develop drugs that modulate DNAK activity, with the potential for treating diseases associated with protein misfolding.

Is there a link between DNAK protein and cardiovascular diseases? 05/15/2020

Some studies suggest that DNAK may play a role in cardiovascular health, and its dysregulation could contribute to heart-related disorders.

Can DNAK protein be used as a biomarker for treatment response? 10/20/2019

Monitoring changes in DNAK protein levels during treatment may provide insights into the effectiveness of therapeutic interventions.

Customer Reviews (3)

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Reviews
11/23/2021

    Equally noteworthy is the remarkable technical support provided by the manufacturer.

    11/16/2018

      Their team of experts has been instrumental in addressing any issues or concerns I have encountered during my experiments.

      08/22/2018

        The DNAK Protein boasts remarkable stability, ensuring its integrity is maintained during storage and experimentation.

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