"TOP1" Related Products

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Recombinant Human TOP1 protein, His-tagged

Cat.No. : TOP1-351H
Product Overview : DNA Topoisomerase-I Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 91,576 Dalton (excluding glycosilation) 102 kDa total mass. The TOP1 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
Source : Insect cells
Species : Human
Tag : His
Form : Sterile Filtered clear solution. Supplied in 16mM HEPES buffer pH-7.5, 400mM sodium chloride, and 20% glycerol.
Purity : Greater than 95% as determined by SDS-PAGE.
Storage : Store at 4 centigrade if entire vial will be used within 2-4 weeks.Store, frozen at -20 centigrade for longer periods of time.Avoid multiple freeze-thaw cycles.
Gene Name : TOP1 topoisomerase (DNA) I [ Homo sapiens ]
Official Symbol : TOP1
Synonyms : TOP1; topoisomerase (DNA) I; DNA topoisomerase 1; type I DNA topoisomerase; TOPI;
Gene ID : 7150
mRNA Refseq : NM_003286
Protein Refseq : NP_003277
MIM : 126420
UniProt ID : P11387
Chromosome Location : 20q12-q13.1
Pathway : Caspase cascade in apoptosis, organism-specific biosystem;
Function : ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA topoisomerase type I activity; chromatin DNA binding; chromatin binding; nucleotide binding; protein binding;

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