"TOP1" Related Products


Recombinant Human TOP1 protein, His-tagged

Cat.No.: TOP1-351H
Product Overview: DNA Topoisomerase-I Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 91,576 Dalton (excluding glycosilation) 102 kDa total mass. The TOP1 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
Source: Insect cells
Species: Human
Tag: His
Form: Sterile Filtered clear solution. Supplied in 16mM HEPES buffer pH-7.5, 400mM sodium chloride, and 20% glycerol.
Purity: Greater than 95% as determined by SDS-PAGE.
Storage: Store at 4 centigrade if entire vial will be used within 2-4 weeks.Store, frozen at -20 centigrade for longer periods of time.Avoid multiple freeze-thaw cycles.
Gene Name: TOP1 topoisomerase (DNA) I [ Homo sapiens ]
Official Symbol: TOP1
Synonyms: TOP1; topoisomerase (DNA) I; DNA topoisomerase 1; type I DNA topoisomerase; TOPI;
Gene ID: 7150
mRNA Refseq: NM_003286
Protein Refseq: NP_003277
MIM: 126420
UniProt ID: P11387
Chromosome Location: 20q12-q13.1
Pathway: Caspase cascade in apoptosis, organism-specific biosystem;
Function: ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA topoisomerase type I activity; chromatin DNA binding; chromatin binding; nucleotide binding; protein binding;

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