"BMF" Related Products

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Recombinant Human BMF, T7-tagged

Cat.No.: BMF-1350H
Product Overview: Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source: E.coli
Species: Human
Tag: T7
Form: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol
Molecular Mass: 15.6 kDa (144aa), confirmed by MALDI-TOF.
Protein length: 1-129aa
AA Sequence: MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP
Endotoxin: < 1.0 eu per 1 microgram of protein (determined by lal
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: BMF Bcl2 modifying factor [ Homo sapiens ]
Official Symbol: BMF
Synonyms: BMF; Bcl2 modifying factor; FLJ00065; Bcl-2-modifying factor
Gene ID: 90427
mRNA Refseq: NM_001003943
Protein Refseq: NP_001003943
MIM: 606266
UniProt ID: Q96LC9
Chromosome Location: 15q14
Pathway: Activation of BH3-only proteins; Activation of BMF and translocation to mitochondria; Androgen receptor signaling pathway
Function: protein binding

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