Recombinant Human BMF, T7-tagged
Cat.No. : | BMF-1350H |
Product Overview : | Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | E.coli |
Species : | Human |
Tag : | T7 |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol |
Molecular Mass : | 15.6 kDa (144aa), confirmed by MALDI-TOF. |
Protein length : | 1-129aa |
AA Sequence : | MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP |
Endotoxin : | < 1.0 eu per 1 microgram of protein (determined by lal |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | BMF Bcl2 modifying factor [ Homo sapiens ] |
Official Symbol : | BMF |
Synonyms : | BMF; Bcl2 modifying factor; FLJ00065; Bcl-2-modifying factor |
Gene ID : | 90427 |
mRNA Refseq : | NM_001003943 |
Protein Refseq : | NP_001003943 |
MIM : | 606266 |
UniProt ID : | Q96LC9 |
Chromosome Location : | 15q14 |
Pathway : | Activation of BH3-only proteins; Activation of BMF and translocation to mitochondria; Androgen receptor signaling pathway |
Function : | protein binding |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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