"DCAMKL2" Related Products

Recombinant Human DCAMKL2, GST-tagged, Active

Cat. No. : DCAMKL2-293H
Product Overview : Recombinant human DCAMKL2 (1-690) was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=105kDa.
Description : DCAMKL2 (also known as doublecortin-like kinase 2 or DCLK2) is a close homologue of doublecortin or DCX which is associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. DCX; DCLK2-null mice display frequent spontaneous seizures that originate in the hippocampus, with most animals dying in the first few months of life.
Source : Sf9 insect cellsusing baculovirus.
Sequence : 1-690.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : DCLK2 doublecortin-like kinase 2 [ Homo sapiens ]
Synonyms : DCLK2; doublecortin-like kinase 2; CL2, CLICK2, DCAMKL2, DCDC3, DCDC3B, DCK2, DKFZp761I032, MGC45428; doublecortin and CaM kinase-like 2; EC 2.7.11.1
Gene ID : 166614
mRNA Refseq : NM_001040260
Protein Refseq : NP_001035350
MIM : 613166
UniProt ID : Q8N568
Chromosome Location : 4q31.23-q31.
Pathway : Bladder cancer; Pathways in cancer
Function : ATP binding; nucleotide binding; protein serine/threonine kinase activity transferase activity

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