| Cat. No. : | DCAMKL2-293H |
| Product Overview : | Recombinant human DCAMKL2 (1-690) was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=105kDa. |
| Description : | DCAMKL2 (also known as doublecortin-like kinase 2 or DCLK2) is a close homologue of doublecortin or DCX which is associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. DCX; DCLK2-null mice display frequent spontaneous seizures that originate in the hippocampus, with most animals dying in the first few months of life. |
| Source : | Sf9 insect cellsusing baculovirus. |
| Sequence : | 1-690. |
| Applications : | Kinase Assay, Western Blot. |
| Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : | DCLK2 doublecortin-like kinase 2 [ Homo sapiens ] |
| Synonyms : | DCLK2; doublecortin-like kinase 2; CL2, CLICK2, DCAMKL2, DCDC3, DCDC3B, DCK2, DKFZp761I032, MGC45428; doublecortin and CaM kinase-like 2; EC 2.7.11.1 |
| Gene ID : | 166614 |
| mRNA Refseq : | NM_001040260 |
| Protein Refseq : | NP_001035350 |
| MIM : | 613166 |
| UniProt ID : | Q8N568 |
| Chromosome Location : | 4q31.23-q31. |
| Pathway : | Bladder cancer; Pathways in cancer |
| Function : | ATP binding; nucleotide binding; protein serine/threonine kinase activity transferase activity |
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