Recombinant Human DMPK, GST-tagged, Active
Cat.No. : | DMPK-295H |
Product Overview : | Recombinant full-length human DMPK was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=105 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | DMPK-295H |
Description : | DMPK (or Myotonic Dystrophy Protein Kinase) is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. DMPK protein has a leucine-rich domain at the N-terminus, a serine/threonine kinase domain in the middle, and a hydrophobic region at the C-terminus. The N-terminus of DMPK plays an important role in DMPK kinase activity, and the C-terminus of DMPK determines the intracellular localization of the protein. Myotonic dystrophy type 1 is an autosomal dominant disease caused by a trinucleotide repeat-expansion, cytosine-thymine-guanine (CTG)n, in the 3" untranslated region of DMPK. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | DMPK dystrophia myotonica-protein kinase [ Homo sapiens ] |
Synonyms : | DMPK; dystrophia myotonica-protein kinase; DM; DM1; DMK; MDPK; DM1PK; MT-PK; DM protein kinase; myotonic dystrophy protein kinase; thymopoietin homolog; myotonin protein kinase A; myotonic dystrophy associated protein kinase; EC 2.7.11.1 |
Gene ID : | 1760 |
mRNA Refseq : | NM_001081560 |
Protein Refseq : | NP_001075029 |
MIM : | 605377 |
UniProt ID : | Q09013 |
Chromosome Location : | 19q13.3 |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
DMPK-2708H | Recombinant Human DMPK Protein, GST-tagged | +Inquiry |
DMPK-0742H | Recombinant Human DMPK Protein (M1-P629), His tagged | +Inquiry |
DMPK-1107R | Recombinant Rhesus Macaque DMPK Protein, His (Fc)-Avi-tagged | +Inquiry |
DMPK-0741H | Recombinant Human DMPK Protein (M1-P629), Tag Free | +Inquiry |
DMPK-2211H | Recombinant Human DMPK Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
DMPK-488HCL | Recombinant Human DMPK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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