"CSF1R" Related Products

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Recombinant Human CSF1R, GST-tagged, Active

Cat. No.: CSF1R-320H
Product Overview: Recombinant human FMS (539-end) was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=76kDa.
Description: FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 (CSF1). FMS is homodimeric that contains a so-called kinase insert domain and is a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. FMS mediates most if not all of the biological effects of CSF1 which control the production, differentiation, and function of cell of the monocyte/macrophage lineage. Mutations in FMS have been associated with providing sustained signals for cell growth and a predisposition to myeloid malignancy.
Source: Sf9 insect cells using baculovirus.
Sequence: 593-end.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: CSF1R colony stimulating factor 1 receptor [ Homo sapiens ]
Synonyms: CSF1R; colony stimulating factor 1 receptor; C-FMS; CD115; CSFR; FIM2; FMS; CD115 antigen; FMS proto-oncogene; McDonough feline sarcoma viral (v-fms) oncogene homolog; macrophage colony stimulating factor I receptor; EC 2.7.10.1; soluble CSF1R variant 1
Gene ID: 1436
mRNA Refseq: NM_005211
Protein Refseq: NP_005202
UniProt ID: P07333
Chromosome Location: 5q33-q35
MIM: 164770
Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Endocytosis; Pathways in cancer
Function: ATP binding; cytokine binding; macrophage colony stimulating factor receptor activity; nucleotide binding; protein homodimerization activity; receptor activity; transferase activity

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