Recombinant Human LYNB, GST-tagged, Active
| Cat.No. : | LYNB-345H |
| Product Overview : | Recombinant full-length human LYN B was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=85kDa. |
- Specification
- Gene Information
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| Cat. No. : | LYNB-345H |
| Description : | LYN is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues. LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction. Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase. |
| Source : | Sf9 insect cellsusing baculovirus. |
| Sequence : | Full-length. |
| Applications : | Kinase Assay, Western Blot. |
| Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : | LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog [ Homo sapiens ] |
| Synonyms : | LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; JTK8; FLJ26625; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog; EC 2.7.10.2 |
| Gene ID : | 4067 |
| mRNA Refseq : | NM_001111097 |
| Protein Refseq : | NP_001104567 |
| MIM : | 165120 |
| UniProt ID : | P07948 |
| Chromosome Location : | 8q13 |
| Pathway : | B cell receptor signaling pathway; Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Hemostasis; Signaling in Immune system; Fc epsilon RI signaling pathway |
| Function : | ATP binding; glycosphingolipid binding; integrin binding; non-membrane spanning protein tyrosine kinase activity; phosphoprotein binding; platelet-derived growth factor receptor binding; receptor signaling protein tyrosine kinase activity; transferase activity; ubiquitin protein ligase binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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