|Cat. No. :
|Product Overview :
||Recombinant Rat Insulin-like Growth Factor Binding Protein-5 (rIGFBP-5) produced inE.coliis a 252 amino acid protein.MW =29 kDa.
||Igfbp5 is one of the six "classical" IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. Rat IGFBP-5 preferentially binds IGF-II and it also binds with high affinity to extracellular matrix components which protect it from proteolysis. Like human IGFBP-5, rat IGFBP-5 has a nuclear targeting sequence.
||> 90% (by SDS PAGE).
|Biological Activity :
||Binds 125I-IGF-I in western ligand blot. Binding affinity for IGF-I - 0.2nM (Biosensor).
|State And Appearance :
||Lyophilized white powder dried from phosphate buffered saline and stored under dry nitrogen at a slight vacuum (-25 kPa).
||At least 2 years at 2 - 4°C (lyophilized).