"CSNK2A1" Related Products

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Recombinant Human CSNK2A1, GST-tagged, Active

Cat. No. : CSNK2A1-283H
Product Overview : Recombinant human full-length CK2alpha1 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=70 kDa.
Description : CK2α is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lymphopro-liferative disease of cattle and in many human cancers. Overexpression of the CK2 catalytic subunit in lymphocytes of transgenic mice leads to T cell lymphoma. The highest CK2α1 activity is found in mouse testicles and brain, followed by spleen, liver, lung, kidney and heart.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : CSNK2A1 casein kinase 2, alpha 1 polypeptide [ Homo sapiens ]
Synonyms : CSNK2A1; casein kinase 2, alpha 1 polypeptide; CKII; CK2A1; casein kinase II alpha 1 subunit; protein kinase CK2; CK2 catalytic subunit alpha; EC 2.7.11.1; OTTHUMP00000029925; OTTHUMP00000029926
Gene ID : 1457
mRNA Refseq : NM_001895
Protein Refseq : NP_001886
UniProt ID : P68400
Chromosome Location : 20p13
MIM : 115440
Pathway : Adherens junction; Tight junction; Wnt signaling pathway
Function : ATP binding; nucleotide binding; protein N-terminus binding; protein serine/threonine kinase activity; transferase activity

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