||Recombinant human full-length CK2alpha1 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=70 kDa.
||CK2α is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lymphopro-liferative disease of cattle and in many human cancers. Overexpression of the CK2 catalytic subunit in lymphocytes of transgenic mice leads to T cell lymphoma. The highest CK2α1 activity is found in mouse testicles and brain, followed by spleen, liver, lung, kidney and heart.
||Sf9 insect cells using baculovirus.
||Kinase Assay, Western Blot.
|Storage And Stability:
||Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.