Recombinant Human CDK5/SNAP25, GST-tagged, Active
Cat.No. : | CDK5/SNAP25-276H |
Product Overview : | Recombinant human full-length CDK5 and p25 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=59 kDa and p25 ~49 kDa. |
- Specification
- Gene Information
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Cat. No. : | CDK5/SNAP25-276H |
Description : | CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CDK5 cyclin-dependent kinase 5 [ Homo sapiens ],SNAP25 synaptosomal-associated protein, 25kDa [ Homo sapiens ] |
Synonyms : | CDK5; cyclin-dependent kinase 5; PSSALRE;Cell division protein kinase 5;EC2.7.11.22; Cyclin-dependent kinase 5; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; Serine/threonine-protein kinase; SNAP25; FLJ23079; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; Super-Protein, bA416N4.2; dJ1068F16.2; synapse protein 25,isoform A; CG40452-PA; Snap25-PA; synapse protein 25, isoform B; CG40452-PB; Snap25-PB; OTTHUMP00000030267; OTTHUMP00000030268; Super protein; Synaptosomal-associated 25 kDa protein; resistance to inhibitors of cholinesterase 4 homolog; synaptosomal-associated protein 25; synaptosomal associated protein, 25kDa; Synaptosomal-associated protein, 25kDa; SNAP-25 (synaptosome-associated protein of 25,000 daltons).EF-hand calcium binding protein; FLJ23079 |
Gene ID : | 1020,6616 |
mRNA Refseq : | NM_001164410,NM_003081 |
Protein Refseq : | NP_001157882,NP_003072 |
UniProt ID : | Q00535,P60880 |
Chromosome Location : | 7q36, 20p12-p11.2 |
MIM : | 123831,600322 |
Pathway : | Alzheimer"s disease; Axon guidance; Opioid Signalling; SNARE interactions in vesicular transport; Botulinum neurotoxicity; Diabetes pathways; Integration of energy metabolism; Synaptic Transmission |
Function : | ATP binding; ErbB-2 class receptor binding; ErbB-3 class receptor binding; acetylcholine receptor activator activity; cyclin-dependent protein kinase activity; nucleotide binding; p53 binding; transferase activity; tau-protein kinase activity;SNAP receptor activity; SNAP receptor activity; soluble NSF attachment protein activity |
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◆ Lysates | ||
CDK5-7626HCL | Recombinant Human CDK5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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