Recombinant Human CAMK2G, C-terminal Truncation, GST-tagged, Active CAMK2G-267H

Recombinant Human CAMK2G, C-terminal Truncation, GST-tagged, Active

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Recombinant Human CAMK2G, C-terminal Truncation, GST-tagged, Active

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Cat. No. : CAMK2G-267H
Product Overview : Recombinant human CAMK2gamma (c-terminal truncation) was expressed by baculovirus inSf9cells using an N-terminal GST tag. MW = 60 kDa.
Description : CAMK2γ is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2γ has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMKG showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype.
Source : Sf9 insect cells using baculovirus.
Sequence : c-terminal truncation.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 2ux0. :

Gene Name : CAMK2G calcium/calmodulin-dependent protein kinase II gamma [ Homo sapiens ]
Synonyms : CAMK2G; calcium/calmodulin-dependent protein kinase II gamma; CAMK; CAMKG; CAMK-II; FLJ16043; MGC26678; CaM kinase II; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; EC 2.7.11.17; OTTHUMP00000019843; OTTHUMP00000019844; CaMK-II subunit gamma; CaM kinase II subunit gamma; CaM-kinase II gamma chain
Gene ID : 818
mRNA Refseq : NM_001222
Protein Refseq : NP_001213
MIM : 602123
UniProt ID : Q13555
Chromosome Location : 10q22
Pathway : Calcium signaling pathway; ErbB signaling pathway; Glioma; GnRH signaling pathway; Long-term potentiation; Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Wnt signaling pathway
Function : ATP binding; calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; transferase activity

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