Recombinant Human SFRS Protein Kinase 3, GST-tagged, Active

• Cat.No.: SRPK3-360H
• Product Overview: Recombinant full-length human MSSK1 was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 98 kDa.

Specification

• Cat. No.: SRPK3-360H
• Description: MSSK1, also known as SRPK3, is a muscle-specific protein kinase belonging to the serine arginine protein kinase family which phosphorylates serine/arginine repeat-containing proteins. Heart and skeletal muscle show high expression of the MSSK1/SRPK3 gene product. SRPK3-null mice display a new entity of type 2 fiber-specific myopathy with a marked increase in centrally placed nuclei. Transgenic mice overexpressing SRPK3 in skeletal muscle show severe myofiber degeneration and early lethality.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: SRPK3 SFRS protein kinase 3 [ Homo sapiens ]
• Synonyms: SRPK3; SFRS protein kinase 3; MSSK1; STK23; MGC102944; serine arginine rich protein-specific kinase 3; serine arginine rich protein-specific kinase 3; serine/threonine kinase 23; muscle-specific serine kinase 1; EC 2.7.11.1; Serine/threonine-protein kinase 23; Serine/threonine-protein kinase SRPK3; MSSK-1
• Gene ID: 26576
• mRNA Refseq: NM_014370
• Protein Refseq: NP_055185
• UniProt ID: Q9UPE1
• Chromosome Location: Xq28
• Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity; transferase activity