"PRKCG" Related Products

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Recombinant Human Protein Kinase C, Gamma, GST-tagged, Active

Cat. No.: PRKCG-404H
Product Overview: Recombinant human full-length PKCgamma was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=105 kDa.
Description: PKCγ is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKCγ is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKCγ and may thereby provide neuroprotection.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: PRKCG protein kinase C, gamma [ Homo sapiens ]
Synonyms: PRKCG; protein kinase C, gamma; PKCG; SCA14; MGC57564; PKC-gamma; Protein kinase C gamma type; EC 2.7.11.13
Gene ID: 5582
mRNA Refseq: NM_002739
Protein Refseq: NP_002730
UniProt ID: P05129
Chromosome Location: 19q13.4
MIM: 176980
Pathway: Calcium signaling pathway; ErbB signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Gap junction; Glioma; Leukocyte transendothelial migration; Long-term depression; Long-term potentiation; MAPK signaling pathway; Melanogenesis; Natural killer cell mediated cytotoxicity; Non-small cell lung cancer; Non-small cell lung cancer; Phosphatidylinositol signaling system; Tight junction; Vascular smooth muscle contraction; Vibrio cholerae infection; Wnt signaling pathway; Synaptic Transmission; Hemostasis
Function: ATP binding; calcium ion binding; nucleotide binding; protein kinase C activity; transferase activity; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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