Recombinant Human SFRS Protein Kinase 1, GST-tagged, Active
Cat.No. : | SRPK1-435H |
Product Overview : | Recombinant full-length human SRPK1 was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 130 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SRPK1-435H |
Description : | SRPK1 is a Ser/Thr protein kinase that has sequence and function similar to SRPK2. In human cancer cells, it was observed that inactivation of SRPK1 induces cellular resistance to anticancer drugs such as cisplatin and bleomycin. SRPK1 phosphorylates serine/arginine-rich (SR) proteins, such as splicing factors ASF/SF2, SC35, and SRp55, in their arginine/serine-rich (RS) domains in vitro. Hence it is believed that SRPK1 plays a key role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | SRPK1 SFRS protein kinase 1 [ Homo sapiens ] |
Synonyms : | SRPK1; SFRS protein kinase 1; SFRSK1; SR protein kinase 1; EC 2.7.11.1; SR-protein-specific kinase 1; Serine/arginine-rich protein-specific kinase 1; Serine/threonine-protein kinase SRPK1 |
Gene ID : | 6732 |
mRNA Refseq : | NM_003137 |
Protein Refseq : | NP_003128 |
MIM : | 601939 |
UniProt ID : | Q96SB4 |
Chromosome Location : | 6p21.3-p21.2 |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
SRPK1-8723M | Recombinant Mouse SRPK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRPK1-1067H | Recombinant Human SRPK1 Protein (M1-S655), Tag Free | +Inquiry |
SRPK1-1066H | Recombinant Human SRPK1 Protein (M1-S655), GST tagged | +Inquiry |
SRPK1-80H | Recombinant Human SRPK1 protein, Flag-tagged, Biotinylated | +Inquiry |
SRPK1-30850TH | Recombinant Human SRPK1 | +Inquiry |
◆ Lysates | ||
SRPK1-1475HCL | Recombinant Human SRPK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket