Recombinant Human PTPRF, GST-tagged, Active
Cat.No. : | PTPRF-469H |
Product Overview : | Recombinant human PTPRF (1275-1897) was expressed inE.Coliusing an N-terminal GST tag. MW=93kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPRF-469H |
Description : | PTPRF or LAR is a member of the protein tyrosine phosphatase family with an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains. PTPRF has been shown to function in the regulation of epithelial cell-cell contacts at adherents junctions as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. |
Source : | E.Coli. |
Sequence : | 1275-1897. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
22q13.33 : | 1p34 |
Gene Name : | PTPRF protein tyrosine phosphatase, receptor type, F [ Homo sapiens ] |
Synonyms : | PTPRF; protein tyrosine phosphatase, receptor type, F; LCA-homolog; OTTHUMP00000008683; OTTHUMP00000008684; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; protein tyrosine phosphatase, receptor type, F polypeptide; receptor-linked protein-tyrosine phosphatase LAR; LAR; FLJ43335; FLJ45062; FLJ45567; EC 3.1.3.48 |
Gene ID : | 5792 |
mRNA Refseq : | NM_002840 |
Protein Refseq : | NP_002831 |
MIM : | 179590 |
UniProt ID : | P10586 |
Pathway : | Adherens junction; Cell adhesion molecules (CAMs); Insulin signaling pathway |
Function : | heparan sulfate proteoglycan binding; heparin binding; hydrolase activit; protein binding; protein kinase binding; transmembrane receptor protein tyrosine phosphatase activity |
Products Types
◆ Recombinant Protein | ||
PTPRF-463H | Recombinant Human PTPRF Protein, His-tagged | +Inquiry |
PTPRF-4499R | Recombinant Rat PTPRF Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRF-7286M | Recombinant Mouse PTPRF Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRF-6106H | Recombinant Human PTPRF Protein (Asp30-Tyr224), His tagged | +Inquiry |
PTPRF-2062H | Recombinant Human PTPRF, GST-tagged | +Inquiry |
◆ Lysates | ||
PTPRF-1439HCL | Recombinant Human PTPRF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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