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Recombinant Human Galactokinase 1, His-tagged

Cat.No. : GALK1-390H
Product Overview : Recombinant human GALK1 (aa. 1-392) produced inE.coliis a 45.1 kDa protein. It was fused to His-Tag at N terminus.
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Cat. No. : GALK1-390H
Description : Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.GALK1 sequence shares the greatest level of conservation, 44.5% identity with that from E. coli and 34.6% amino acid identity with the product of the human GALK2 gene.
Source : E.coli.
Purity : 95%.
Preparation : 0.1mg/0.67 ml.
Tested Application : E, WB, MS.
Buffer : 10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM.
Species Reactivity : n/aH.
Storage : Store at -70°C with any protein, exposing GALK1 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Pathways : Amino sugar and nucleotide sugar metabolism; Galactose metabolism; Metabolic pathways; Metabolism of carbohydrates
Gene Name : GALK1 galactokinase 1 [ Homo sapiens ]
Synonyms : galactokinase 1; GK1; GALK; GALK1; EC 2.7.1.6; Galactose kinase
Gene ID : 2584
mRNA Refseq : NM_000154
Protein Refseq : NP_000145
MIM : 604313
UniProt ID : P51570
Chromosome Location : 17q24
Function : ATP binding; galactokinase activity; galactose binding; kinase activity; nucleotide binding; protein binding; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Are there different isoforms or variants of GALK1? 03/04/2022

Yes, there may be different subtypes or variants of GALK1 that may have different biological functions.

How do these different subtypes or variants function in cells? 03/18/2021

Different subtypes or variants may play different roles in cells, and the specific mechanisms need further research.

What are the effects of regulating GALK1 expression on cells? 03/16/2021

Regulating the expression of GALK1 may affect the glycolysis process and energy metabolism of cells.

What is the mechanism of action of these drugs? 12/28/2020

The mechanism of action of these drugs may include inhibition of GALK1 activity, regulation of its expression level, etc.

Is GALK1 involved in other biological processes? 08/01/2020

In addition to glycolysis, GALK1 may also be involved in other biological processes, such as cell signaling.

How to regulate the expression of GALK1 experimentally? 03/01/2020

The expression of GALK1 can be regulated by gene knockout, transgene and other technologies.

Customer Reviews (3)

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Reviews
09/06/2022

    The production process of GALK1 is stable and reliable, with high batch refolding.

    07/21/2022

      GALK1 is pure and has no other proteins or impurities.

      04/28/2021

        GALK1 has good stability in solution and is not easy to aggregate or deactivate.

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