Recombinant Human ARSB

• Cat.No.: ARSB-26104TH
• Product Overview: Recombinant fragment of Human ARSB with N-terminal proprietary tag. Predicted MW 36.63 kDa.

Specification

• Description: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Protein length: 100 amino acids
• Molecular Weight: 36.630kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: FGYLLGSEDYYSHERCTLIDALNVT RCALDFRDGEEVATGYKNMYSTNIF TKRAIALITNHPPEKPLFLYLALQS VHEPLQVPEEYLKPYDFIQDKNRHH
• Sequence Similarities: Belongs to the sulfatase family.

Gene Information

• Gene Name: ARSB arylsulfatase B [ Homo sapiens ]
• Official Symbol: ARSB
• Synonyms: ARSB; arylsulfatase B
• Gene ID: 411
• mRNA Refseq: NM_000046
• Protein Refseq: NP_000037
• MIM: 611542
• Uniprot ID: P15848
• Chromosome Location: 5p11-q13
• Pathway: Chondroitin sulfate degradation, organism-specific biosystem; Chondroitin sulfate degradation, conserved biosystem; Dermatan sulfate degradation, organism-specific biosystem; Dermatan sulfate degradation, conserved biosystem; Glycosaminoglycan degradation, organism-specific biosystem
• Function: N-acetylgalactosamine-4-sulfatase activity; arylsulfatase activity; catalytic activity; hydrolase activity; metal ion binding