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Recombinant Human BAG1

Cat.No. : BAG1-26063TH
Product Overview : Recombinant fragment, corresponding to amino acids 72-345 of Human Bag1 with N-terminal proprietary tag, 66kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Source : E. coli
Tissue specificity : Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tu
Form : Liquid
Storage buffer : Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM MOPS, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Contains 1 BAG domain.Contains 1 ubiquitin-like domain.
Gene Name : BAG1 BCL2-associated athanogene [ Homo sapiens ]
Official Symbol : BAG1
Synonyms : BAG1; BCL2-associated athanogene; BAG family molecular chaperone regulator 1;
Gene ID : 573
mRNA Refseq : NM_001172415
Protein Refseq : NP_001165886
MIM : 601497
Uniprot ID : Q99933
Chromosome Location : 9p12
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function : chaperone binding; protein binding; receptor signaling protein activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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