Human BAG1 Knockdown Cell Lysate

• Cat.No.: BAG1-065HKCL
• Product Overview: WB-validated BAG1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 39 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg BAG1 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: BAG1 BCL2-associated athanogene [ Homo sapiens (human) ]
• Official Symbol: BAG1
• Synonyms: BAG1; BCL2-associated athanogene; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-binding protein; receptor-associated protein, 46-KD; Bcl-2 associating athanogene-1 protein; glucocortoid receptor-associated protein RAP46; HAP; RAP46
• Gene ID: 573
• mRNA Refseq: NM_001172415
• Protein Refseq: NP_001165886
• MIM: 601497
• UniProt ID: Q99933