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Recombinant Human BAK1 Protein, GST-tagged

Cat.No. : BAK1-26166TH
Product Overview : Recombinant Human ATF6B(1 a.a. - 211 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
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Description : The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 49.8 kDa
Protein length : 1 a.a. - 211 a.a.
AA Sequence : MASGQGPGPPRQECGEPALPSASEE QVAQDTEEVFRSYVFYRHQQEQEAE GVAAPADPEMVTLPLQPSSTMGQVG RQLAIIGDDINRRYDSEFQTMLQHL QPTAENAYEYFTKIATSLFESGINW GRVVALLGFGYRLALHVYQHGLTGF LGQVTRFVVDFMLHHCIARWIAQRG GWVAALNLGNGPILNVLVVLGVVLL GQFVVRRFFKS
Applications : Enzyme-linked Immunoabsorbent; Assay Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : BAK1 BCL2-antagonist/killer 1 [ Homo sapiens ]
Official Symbol : BAK1
Synonyms : BAK1; BCL2-antagonist/killer 1; CDN1; bcl-2 homologous antagonist/killer; BAK; BCL2L7; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; apoptosis regulator BAK; pro-apoptotic protein BAK; BAK-LIKE; MGC3887; MGC117255;
Gene ID : 578
mRNA Refseq : NM_001188
Protein Refseq : NP_001179
MIM : 600516
UniProt ID : Q16611

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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