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Recombinant Human BCAM

Cat.No. : BCAM-27252TH
Product Overview : Recombinant fragment of Human CD239 with N terminal proprietary tag; Predicted MW 36.63 kDa
  • Specification
  • Gene Information
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Description : Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : EVRLSVPPLVEVMRGKSVILDCTPT GTHDHYMLEWFLTDRSGARPRLASA EMQGSELQVTMHDTRGRSPPYQLDS QGRLVLAEAQVGDERDYVCVVRAGA
Sequence Similarities : Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Gene Name : BCAM basal cell adhesion molecule (Lutheran blood group) [ Homo sapiens ]
Official Symbol : BCAM
Synonyms : BCAM; basal cell adhesion molecule (Lutheran blood group); basal cell adhesion molecule (Lu and Au blood groups) , LU, Lutheran blood group (Auberger b antigen included); basal cell adhesion molecule; CD239;
Gene ID : 4059
mRNA Refseq : NM_001013257
Protein Refseq : NP_001013275
MIM : 612773
Uniprot ID : P50895
Chromosome Location : 19q12-q13
Function : laminin binding; laminin receptor activity; transmembrane signaling receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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