Recombinant Human BCL11B, His-tagged

• Cat.No.: BCL11B-28027TH
• Product Overview: Recombinant fragment, corresponding to amino acids 387-823 of Human Ctip2 with an N-terminal His Tag, approximately 58kDa

Specification

• Description: This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:reconstitution with 138 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASS PEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDE EEEEEEEELLLENESRPESSFSMDSELSRNRENGGGGV PGVPGAGGGAAKALADEKALVLGKVMENVGLGALPQYGEL LADKQKRGAFLKRAAGGGDAGDDDDAGGCGDAGAGGAV NGRGGGFAPGTEPFPGLFPRKPAPLPSPGLNSAAKRIK VEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGF TDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGR SGTASGGSTPHLGGPGPGRPSSKEGRRSDTCEYCGKVF KNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKT HGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLT NDVKIEQAERS

Gene Information

• Gene Name: BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) [ Homo sapiens ]
• Official Symbol: BCL11B
• Synonyms: BCL11B; B-cell CLL/lymphoma 11B (zinc finger protein); ZNF856B; B-cell lymphoma/leukemia 11B; CTIP 2; CTIP2; hRIT1 alpha
• Gene ID: 64919
• mRNA Refseq: NM_022898
• Protein Refseq: NP_075049
• MIM: 606558
• Uniprot ID: Q9C0K0
• Chromosome Location: 14q32
• Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; metal ion binding